Getting My megatomi.com To Work
Getting My megatomi.com To Work
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Our new Apparent+ tissue clearing system is the only technique that delipidates samples without any adjust in morphology and with small influence on structural integrity.
Megatome is often a vibrating microtome meant to section a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform floor profile, together with small tissue damage and knowledge decline.
Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is designed for accuracy: the blade vibrates at a higher frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.
SE works by using a rotational electrical discipline to disperse hugely electromobile molecules (like antibodies or surfactant micelles) in the course of a porous sample with no harmful electrically charged structures throughout the tissue. This allows 2-4 day clearing of intact organs,
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Megatome can be a novel microtome that allows for top-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with negligible tissue injury and information reduction.
eFLASH megatomi.com is really a swift tissue labeling approach which allows for uniform complete-organ staining in 20 rounds of labeling.
The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace all over intact tissue volumes, although its modular design lets you upgrade and personalize unique elements.
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SHIELD avoids the variability of hydrogel embedding and the information loss from PFA preservation, safeguarding specimens for many rounds of processing.
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Our novel Protect tissue preservation technique forms intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.